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Eleuthero, Siberian Ginseng
(Eleutherococcus senticosus)
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| Introduction |
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| Eleuthero is one of the top selling herbal products in the United States. It is a member of the ginseng family, but it is of a different genus than other popular ginsengs. The use of eleuthero root dates back 2,000 years in the records of Chinese medicine when it was used for respiratory tract infections, as well as colds and flu. The Chinese also believed that eleuthero provided energy and vitality. In Russia, the people of Siberia originally used it to increase physical performance and quality of life. |
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| Reported Uses |
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Eleuthero has been reported to increase stamina and endurance and protect the body systems against stress-induced illness and fatigue.(1, 2, 3) Scientists refer to eleuthero as an adaptogen, meaning it has the ability to boost nonspecific resistance of the body to a wide range of chemical, physical, psychological, and biological stressors.
The adaptogenic properties of eleuthero have been extensively investigated in Russia. Studies conducted there have found that ginseng may offer a wide range of benefits. Some of these include:
- Increased physical endurance under stress.(4)
- Increased mental alertness.(5)
- Increased athletic performance.(6)
- Protection from toxins.(7, 8)
- Support of cardiovascular health.(9)
- Enhancement of immunity.(10, 11)
- Support of the endocrine system.(12, 13)
- Enhanced vision.(14)
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| Dosage Info |
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| Dosage Range |
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Most Common Dosage |
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Dosage Forms |
| 100-200mg (standardized extract), 2-3 times daily. A regimen of 4 weeks on, 2 weeks off is recommended for maximum benefits. |
200mg (standardized extract), 2 times a day. A regimen of 4 weeks on, 2 weeks off is recommended for maximum benefits. |
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| Toxicities & Precautions |
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| Be sure to tell your pharmacist, doctor, or other health care providers about any dietary supplements you are taking. There may be a potential for interactions or side effects. |
General This dietary supplement is considered safe when used in accordance with proper dosing guidelines. |
Health Conditions If you have hypertension, long term use of this dietary supplement is not recommended.(15) If you have a bleeding disorder, an active infection or fever talk to your doctor before taking this dietary supplement.
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Side Effects
Side effects are possible with any dietary supplement. This dietary supplement may cause hypertension, insomnia, irritability, anxiety and elevated heart rate.(16) Tell your doctor if these side effects become severe or do not go away.
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Pregnancy/Breast-Feeding This dietary supplement should not be used if you are pregnant or breast-feeding an infant.(17) |
Age Limitations To date, the medical literature has not reported any adverse effects specifically related to the use of this dietary supplement in children. Since young children may have undiagnosed allergies or medical conditions, this dietary supplement should not be used in children under 10 years of age unless recommended by a physician. |
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| Footnotes |
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1 Fulder SJ. Ginseng and the Hypothalamic-pituitary Control of Stress. Am J Chin Med. 1981;9(2):112-18.
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2 Asano K, et al. Effect of Eleutherococcus senticosus Extract on Human Physical Working Capacity. Planta Med. 1986;3:175-77.
3 Hartz AJ. Randomized controlled trial of Siberian ginseng for chronic fatigue. Psychol Med. 2004 Jan;34(1):51-61.
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4 Hikino H, et al. Isolation and Hypoglycemic Activity of Eleutherans A, B, C, D, E, F and G: Glycans of Eleutherococcus senticosus Roots. J Nat Prod. 1986;49(2):293-97.
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5 Farnsworth NR, et al. Siberian Ginseng (Eleutherococcus senticosus): Current Status as an Adaptogen. In: Economics and Medicinal Plant Research. Vol 1. London: Academic Press; 1985:155-209.
6 Hikino H, et al. Isolation and Hypoglycemic Activity of Eleutherans A, B, C, D, E, F and G: Glycans of Eleutherococcus senticosus Roots. J Nat Prod. 1986;49(2):293-97.
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7 Minkova M, et al. Effect of Eleutherococcus Extract on the Radioprotective Action of Adeturone. Acta Physiol Pharmacol Bulg. 1987;13(4):66-70.
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8 Tenchova VB, et al. Changes in Hemopoiesis in the Rat as a Result of Combined Exposure to Acceleration, Irradiation and Radiation-modifying Agents. Kosm Biol Aviakosm Med. 1987;21(2):85-86.
9 Maslova LV, et al. Cardioprotective Effects of Adaptogens of Plant Origin. Biull Eksp Biol Med. 1993;115(3):269-71.
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10 Bohn B, et al. Flow-cytometric Studies with Eleutherococcus senticosus Extract as an Immunomodulatory Agent. Arzneimittelforschung. 1987;37(10):1193-96.
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11 Kupin VI, et al. Stimulation of the Immunological Reactivity of Cancer Patients by Eleutherococcus Extract. Vopr Onkol. 1986;32(7):21-26.
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12 Farnsworth NR, et al. Siberian Ginseng (Eleutherococcus senticosus): Current Status as an Adaptogen. In: Economics and Medicinal Plant Research. Vol 1. London: Academic Press; 1985:155-209.
13 Filaretov AA, et al. Effect of Adaptogens on the Activity of the Pituitary-adrenocortical System in Rats. Biull Eksp Biol Med. 1986;101(5):573-74.
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14 Sosnova TL. The Effect of Eleutherococcus spinosus on the Color Discrimination Function of the Visual Analyzer in Persons with Normal Trichromatic Vision. Vestn Oftalmol. 1969;82(5):59-61.
15 PDR for Herbal Medicines, 2nd ed. Montvale, NJ: Medical Economics Company; 2000:694.
16 Farnsworth NR, et al. Siberian Ginseng (Eleutherococcus senticosus): Current Status as an Adaptogen. In: Economics and Medicinal Plant Research. Vol 1. London: Academic Press; 1985:155-209.
17 Chan LY, et al. An in-vitro study of ginsenoside Rb1-induced teratogenicity using a whole rat embryo culture model. Hum Reprod. Oct 2003;18(10):2166-8.
View Abstract
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