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| Introduction |
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| Chloride is one of the body's three major electrolytes (the other two being sodium and potassium). Electrolytes are involved in intracellular osmosis, which means that they control the flow of body fluids into and out of tissues and cells.
Because the primary dietary source of chloride is table salt (sodium chloride), most people in the United States receive enough chloride in their diet. Chloride also occurs abundantly in vegetables and animal foods.
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| Reported Uses |
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As part of its role as an electrolyte, chloride controls the distribution and balance of water throughout the body. Chloride also helps maintain pH balance throughout the body. As a component of hydrochloric acid in the stomach, chloride is necessary for the processes of digestion. Chloride also plays a role in assisting the lungs in their job of exhaling carbon dioxide. Lastly, chloride plays a key role in nerve transmission and muscle activity.
In addition to these overall benefits, chloride may have several targeted clinical applications according to scientific studies. First, it is often used in medications that treat diarrhea.(1, 2, 3) Second, chloride's role as an electrolyte means that it is commonly used in preparations to treat dehydration.(4, 5, 6) Such preparations are also beneficial to athletes who wish to replenish body fluids after strenuous exercise. Finally, chloride is often used as part of preparations to treat a blood condition that involves low plasma volume.(7)
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| Dosage Info |
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| Dosage Range |
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Most Common Dosage |
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Dosage Forms |
| Estimated safe and adequate intake of chloride for adults is from 1.5-5 grams daily. |
Chloride is available in high amounts from dietary intake. It is seldom taken as a nutritional supplement. |
Tablets, granules, powder and depending on the salt, as an injection (Rx only). |
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| Toxicities & Precautions |
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| Be sure to tell your pharmacist, doctor, or other health care providers about any dietary supplements you are taking. There may be a potential for interactions or side effects. |
General
This dietary supplement is considered safe when used in accordance with proper dosing guidelines.
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Pregnancy/Breast-Feeding
To date, the medical literature has not reported any adverse effects related to fetal development during pregnancy or to infants who are breast-fed. Proper nutrition is essential during pregnancy for the healthy development of the fetus. Numerous vitamins and minerals are a vital part of proper nutrition. If you are pregnant, think you might be pregnant, trying to get pregnant, or breast-feeding an infant, talk to your healthcare professional about supplementing your diet with appropriate vitamins and minerals. |
Age Limitations
To date, the medical literature has not reported any adverse effects specifically related to the use of this dietary supplement in children. Vitamins and minerals are an essential part of proper growth and development. Talk to your healthcare professional about the appropriate use of vitamins and minerals in children. Do not use any vitamin or mineral in children under 2 years of age unless first discussed with your healthcare professional. |
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| Footnotes |
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1 Mahalanabis D, et al. Hypotonic Oral Rehydration Solution in Acute Diarrhoea: A Controlled Clinical Trial. Acta Paediatr. Mar1995;84(3):289-93.
View Abstract
2 Kriemler S, et al. Preventing Dehydration in Children with Cystic Fibrosis who Exercise in the Heat. Med Sci Sports Exerc. Jun1999;31(6):774-79.
View Abstract
3 Hoglund P, et al. Distinct outcomes of chloride diarrhoea in two siblings with identical genetic background of the disease: implications for early diagnosis and treatment. Gut. May2001;48(5):724-7.
View Abstract
4 Holmberg C. Congenital Chloride Diarrhoea. Clin Gastroenterol. Jul1986;15(3):583-602.
View Abstract
5 Banister A, et al. Treatment of Hypernatraemic Dehydration in Infancy. Arch Dis Child. Mar1975;50(3): 179-86.
View Abstract
6 Kriemler S, et al. Preventing dehydration in children with cystic fibrosis who exercise in the heat. Med Sci Sports Exerc. Jun1999;31(6):774-9.
View Abstract
7 Greenleaf JE, et al. Sodium Chloride-citrate Beverages Attenuate Hypovolemia in Men Resting 12 h at 2800 m Altitude. Aviat Space Environ Med. Oct1998;69(10):936-43.
View Abstract
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This information is educational in context and is not to be used to diagnose, treat or cure any disease. Please consult your licensed health care practitioner before using this or any medical information.
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