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Hawthorn
(Crataegus laevigata, Crataegus oxyacantha, Crataegus monogyna)
 
 Plant Part Used  
Flower, leaf, and berry
 Introduction Back to Top
Historically, hawthorn was used by Roman physicians as a heart drug in the first century A.D. The literature from that period focuses on its symbolic use of hawthorn for religious rites and political ceremonies. During the Middle Ages, hawthorn was used for the treatment of "dropsy," or congestive heart failure.

Today, extracts made from the flower, leaf, and berry of the hawthorn plant have been used extensively in Europe to treat a variety of circulatory disorders, including high blood pressure.

 Reported Uses Back to Top
Interactions
Drug/Herb Interactions
Antiarrhythmic medications
ACE inhibitors
Antihypertensive medications
Cardiac glycosides
Researchers think that hawthorn may be able to regulate both low and high blood pressure. One of its key components, bioflavinoids, are thought to dilate the blood vessels.(1) This leads to hawthorn's use in preventing angina attacks. Its function as a mild diuretic may be the key to its blood pressure-lowering effects.

Hawthorn has also been evaluated in people with NYHA class II heart failure.(2) In a study of 132 individuals, standardized hawthorn extract compared favorably to captopril, a member of a class of prescription medications known as ACE-inhibitors.(3) Another study involving 136 patients, the hawthorn group showed improvement in the areas of heart function evaluated, whereas the placebo group did not.

Other key components of hawthorn are believed to support heart and circulatory system health including heartbeat, blood flow, control of artherosclerotic plaque and more.(4, 5, 6, 7) Because hawthorn also promotes healthy collagen production, supportive effects may also extend to such disorders as Raynaud's disease and varicose veins.(8)

 Dosage Info Back to Top
Dosage Range Most Common Dosage Standardization
250 mg (standardized extract), 1 to 3 times a day.

Berry: 300 mg to 1 g, 3 times a day.

Tincture: 1-2 ml, 3 times a day.

Crude: 200-500 mg daily.

Leaf and Flowers Extract: 160-900 mg = to 3.5-19.8 mg flavonoids daily.

250 mg (standardized extract), 3 times a day.

Berry: 300 mg, 3 times a day.

Tincture 1 ml, 3 times a day.

Crude: 200 mg daily.

Leaf and Flowers Extract: 160 mg = to 3.5 mg flavonoids daily.

The most current available medical and scientific literature indicates that this dietary supplement should be standardized to 2% vitexin and/or 20% procyanidins per dose. European products standardized to 2.2% flavonoids.
 
*Standardization represents the complete body of information and controls that serve to enhance the batch to batch consistency of a botanical product, including but not limited to the presence of a marker compound at a defined level or within a defined range.(9)
 Toxicities & Precautions Back to Top
Be sure to tell your pharmacist, doctor, or other health care providers about any dietary supplements you are taking. There may be a potential for interactions or side effects.
General
This dietary supplement is considered safe when used in accordance with proper dosing guidelines.(10)
Pregnancy/Breast-Feeding
This dietary supplement should not be used in pregnant women.(11)

This dietary supplement should not be used if you are breast-feeding an infant without first consulting a physician.

Age Limitations
To date, the medical literature has not reported any adverse effects specifically related to the use of this dietary supplement in children. Since young children may have undiagnosed allergies or medical conditions, this dietary supplement should not be used in children under 10 years of age unless recommended by a physician.
 Footnotes Back to Top
1 Wagner H, et al. Cardioactive Drugs IV. Cardiotonic Amines from Crataegus oxyacantha. Planta Medica. 1982;45:99-101.
2 Degenring FH, Suter A, Weber M, Saller R. A randomised double blind placebo controlled clinical trial of a standardised extract of fresh Crataegus berries (Crataegisan) in the treatment of patients with congestive heart failure NYHA II. Phytomedicine. 2003;10(5):363-9.
View Abstract
3 Tauchert M, Ploch M, Huebner WD. Effectiveness of Hawthorn Extract LI132 Compared with the ACE Inhibitor Captopril: Multicenter double-blind study with 132 NYHA Stage II. Muench Med Wochenschr. 1994;136(supp):S27-S33.
4 Taskov M. On the Coronary and Cardiotonic Action of Crataemon. Acta Physiol Pharmacol Bulg. 1977;3(4):53-57.
View Abstract
5 Petkov E, et al. Inhibitory Effect of Some Flavonoids and Flavonoid Mixtures on Cyclic AMP Phosphodiesterase Activity of Rat Heart. Planta Medica. 1981;43:183-86.
6 Uchida S, et al. Inhibitory Effects of Condensed Tannins on Angiotensin Converting Enzyme. Jap J Pharmacol. 1987;43(2):242-46.
View Abstract
7 Wegrowski J, Robert AM, Moczar M. The Effect of Procyanidolic Oligomers on the Composition of Normal and Hypercholesterolemic Rabbit Aortas. Biochem Pharm. 1984;33:3491-97.
View Abstract
8 Kuhnau J. The Flavonoids. A Class of Semi-essential Food Components. Their Role in Human Nutrition. Wld Rev Nutr Diet. 1976;24:117-91.
9 American Herbal Products Association. Use of Marker Compounds in Manufacturing and Labeling Botanically Derived Dietary Supplements. Silver Spring, MD: American Herbal Products Association; 2001.
10 Ammon HPT, et al. Crataegus, Toxicology and Pharmacology. Part I: Toxicity. Planta Medica. 1981;43(2):105-20.
11 Ammon HPT, et al. Crataegus, Toxicology and Pharmacology. Part I: Toxicity. Planta Medica. 1981;43(2):105-20.

 

About Hawthorn
Introduction
Reported Uses
Dosage Info
Precaution
Footnotes

Health Conditions Related to Hawthorn
Aging
Angina
Cardiovascular Disease
Congestive Heart Failure (CHF)
Hypertension
Hypotension
Raynaud's Disease
Stroke

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This information is educational in context and is not to be used to diagnose, treat or cure any disease. Please consult your licensed health care practitioner before using this or any medical information.