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Red Yeast Rice
(Monascus purpureus Went)
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| Plant Part Used |
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| Fermented rice |
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| Introduction |
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| Reported Uses |
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This ancient remedy has demonstrated an exciting potential for treating a patently modern disorder: high cholesterol. Recent studies have identified red yeast rice as a beneficial supplement for maintaining a healthy balance of cholesterol and related fatty lipids in the body. Studies have reported lowering of LDL and triglycerides (the so-called "bad" cholesterol compounds) while increasing HDL ("good" cholesterol).(1, 2, 3)
Additional research has suggested that red yeast rice may rival prescription HMG-CoA reductase inhibiting cholesterol-lowering medications in the control of serum cholesterol and triglyceride levels by the same manner within the body.(4)
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| Dosage Info |
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| Dosage Range |
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Most Common Dosage |
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Standardization |
| 600-1,200mg, 2 times a day. The dose should not exceed 4,800mg (4.8 grams) in a 24-hour period. |
Two 600mg capsules, 2 times a day, taken in the morning and the evening with food. The dose should not exceed 4,800mg (4.8 grams) in a 24-hour period. |
The most current available medical and scientific literature indicates that this dietary supplement should be standardized to 0.4% total HMG-CoA reductase inhibitors per dose. |
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*Standardization represents the complete body of information and controls that serve to enhance the batch to batch consistency of a botanical product, including but not limited to the presence of a marker compound at a defined level or within a defined range.(5)
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| Toxicities & Precautions |
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| Be sure to tell your pharmacist, doctor or other health care providers about any dietary supplements you are taking. There may be a potential for interactions or side effects. |
General
All individuals should have their liver function monitored by a physician during use.(6)
This dietary supplement is considered safe when used in accordance with proper dosing guidelines. |
Allergy
Some individuals experience an allergic reaction when taking this dietary supplement. Do not use this dietary supplement if you are allergic or hypersensitive to rice products or yeast. Call your doctor or seek medical attention if you have fast or irregular breathing, skin rash, hives or itching.
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Health Conditions
If you have a liver disease, a serious infection, history of an organ transplant or have undergone a recent major surgery, talk to your doctor before taking this dietary supplement.
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Side Effects
Side effects are possible with any dietary supplement. Although rare and mild, this dietary supplement may cause heartburn, abdominal flatulence, and dizziness.(7) In addition, the product may exacerbate pre-existing gastritis. Tell your doctor if these side effects become severe or do not go away. Discontinue use and contact your physician if you experience unexplained muscle pain, tenderness or weakness, especially if accompanied by flu-like symptoms.
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Pregnancy/Breast-Feeding
This dietary supplement should not be used in pregnant women.
This dietary supplement should not be used if you are breast-feeding an infant without first consulting a physician.
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Age Limitations
This dietary supplement should not be used in individuals less than 20 years of age unless recommended by a physician.
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| Footnotes |
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1 Bonovitch K, Colfer H, Davidson M, et al. A Multi-center Center Study of Cholestin in Subjects with Elevated Cholesterol. Abstracts of the National Medical Ass Scientific Assembly. Aug1998:1-6.
2 Wang J, Lu Z, Chi J, et al. Multicenter Clinical Trial of the Serum Lipid-lowering Effects of a Monascus purpureus (red yeast) Rice Preparation from Traditional Chinese Medicine. Current Therapeutic Research. 1997;58):964-78.
3 Shen Z, Yu P, Sun M, et al. A Prospective Study on Zhitai Capsule in the Treatment of Primary Hyperlipidemia. National Medical J of China. 1996;76:156-57.
4 Wei J, Yang H, Zhang C, et al. A Comparative Study of Xuezhikang and Mevalotin in Treatment of Essential Hyperlipidemia. Chinese J of New Drugs. 1997;(6):265-68.
5 American Herbal Products Association. Use of Marker Compounds in Manufacturing and Labeling Botanically Derived Dietary Supplements. Silver Spring, MD: American Herbal Products Association; 2001.
6 Wang J, Su M, Lu Z, et al. Clinical Trial of Extract of Monascus purpureus (red yeast) in the Treatment of Hyperlipidemia. Chinese J of Experimental Therapeutics for Prepared Chinese Med. 1995(1):1-5.
7 Wang J, Su M, Lu Z, et al. Clinical Trial of Extract of Monascus purpureus (red yeast) in the Treatment of Hyperlipidemia. Chinese J of Experimental Therapeutics for Prepared Chinese Med. 1995(1):1-5.
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Copyright © 2000-2009 NHIOnDemand All rights reserved.
www.nhiondemand.com
This information is educational in context and is not to be used to diagnose, treat or cure any disease. Please consult your licensed health care practitioner before using this or any medical information.
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