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Schisandra
(Schisandra chinensis)
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| Plant Part Used |
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| Berry |
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| Introduction |
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| Use of the schisandra berry dates back centuries when Chinese medical practitioners found it useful for support of the kidneys and as a sedative. In Russia, schisandra has been used to increase the body's natural ability to fight off disease and stresses from chemical, physical, mental and environmental sources. |
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| Reported Uses |
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Schisandra has historically been used to treat cough and wheezing, spontaneous sweating, chronic diarrhea, insomnia and forgetfulness. But recent research has focused on its potential for supporting liver health.(1, 2) Studies indicate that it may be effective in protecting the liver from harmful toxins and that it may stimulate liver repair.(3, 4) Related studies have suggested that schisandra may aid in the treatment of certain types of hepatitis.
Other studies have suggested that schisandra may inhibit the growth of skin and liver tumors.(5)
Schisandra has been reported to increase human endurance and mental and physical performance. Other historical uses include use to improve mental efficiency and sensitivity of sight, hearing and touch.
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| Dosage Info |
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| Dosage Range |
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Most Common Dosage |
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Standardization |
| 100-200mg (standardized extract), 2 times a day. |
100mg (standardized extract), 2 times a day. |
The most current available medical and scientific literature indicates that this dietary supplement should be standardized to a minimum 9% schisandrins per dose. |
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*Standardization represents the complete body of information and controls that serve to enhance the batch to batch consistency of a botanical product, including but not limited to the presence of a marker compound at a defined level or within a defined range.(6)
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| Toxicities & Precautions |
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| Be sure to tell your pharmacist, doctor or other health care providers about any dietary supplements you are taking. There may be a potential for interactions or side effects. |
General This dietary supplement is considered safe when used in accordance with proper dosing guidelines.(7) |
Health Conditions If you have liver disease, liver damage or an active infection, contact your doctor before taking this dietary supplement. |
Pregnancy/Breast-Feeding This dietary supplement should not be used in pregnant women.(8)
This dietary supplement should not be used if you are breast-feeding an infant without first consulting a physician.
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Age Limitations To date, the medical literature has not reported any adverse effects specifically related to the use of this dietary supplement in children. Since young children may have undiagnosed allergies or medical conditions, this dietary supplement should not be used in children under 10 years of age unless recommended by a physician. |
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| Footnotes |
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1 Maeda S, et al. Effects of Gomisin A on Liver Functions in Hepatotoxic Chemicals-treated Rats. Jpn J Pharmacol. Aug1985;38(4): 347-53.
View Abstract
2 Kubo S, et al. Effect of Gomisin A (TJN-101) on Liver Regeneration. Planta Med. Dec1992;58(6):489-92.
View Abstract
3 Shiota G, et al. Rapid Induction of Hepatocyte Growth Factor mRNA after Administration of Gomisin A, a Lignan Component of Shizandra Fruits. Res Commun Mol Pathol Pharmacol. Nov1996;94(2):141-46.
View Abstract
4 Ohtaki Y, et al. Deoxycholic Acid as an Endogenous Risk Factor for Hepatocarcinogenesis and Effects of Gomisin A, a Lignan Component of Schizandra Fruits. Anticancer Res. Mar1996;16(2):751-55.
View Abstract
5 Yasukawa K, et al. Gomisin A Inhibits Tumor Promotion by 12-O-tetradecanoylphorbol-13-acetate in Two-stage Carcinogenesis in Mouse Skin. Oncology. 1992;49(1):68-71.
View Abstract
6 American Herbal Products Association. Use of Marker Compounds in Manufacturing and Labeling Botanically Derived Dietary Supplements. Silver Spring, MD: American Herbal Products Association; 2001.
7 Leung A, et al. Encylopedia of Common Natural Ingredients Used in Foods, Drugs, and Cosmetics. New York: Wiley-Interscience Publication; 1996:469-71.
8 Upton R. Schisandra Berry: Analytical, Quality Contol, and Therapeutic Monograph. Santa Cruz, CA: American Herbal Pharmacopoeia; 1999.
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Copyright © 2000-2009 NHIOnDemand All rights reserved.
www.nhiondemand.com
This information is educational in context and is not to be used to diagnose, treat or cure any disease. Please consult your licensed health care practitioner before using this or any medical information.
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