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Asthma


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Introduction
Asthma is defined by the American Thoracic Society as a disease characterized by increased responsiveness of the trachea and bronchi to various stimuli and manifested by a widespread narrowing of the airways.(1) Asthma is a disease that affects a person's essential ability to breathe, and is one of the most demanding pathologies on the human being, both physically and mentally.

Asthma is a chronic lung disease characterized by bronchoconstriction that is reversible, airway inflammation resulting from edema in the lining of the bronchial tubes, and increased airway responsiveness to a variety of stimuli. Symptoms usually occur during the first five years of life in 65 percent of the patients. A key feature of the disease is a hyper-responsiveness of the airways to various triggering stimuli, which causes the airways to react to irritation with severe bronchospasm and inflammation, resulting in symptoms of wheezing, shortness of breath, and tachycardia.

There are two classifications of asthma, intrinsic and extrinsic. Intrinsic asthma usually develops in adulthood and may begin with risk factors such as cold air, exercise, or emotional trauma. Extrinsic, or atopic asthma, is considered an immunologically mediated condition with a rise in serum IgE.


Allergic Causes of Asthma Attacks (2)
  • Grass/Tree/Plant pollens
  • Animal dander
  • Cat hair, saliva, urine
  • Dog hair, saliva
  • Cockroaches
  • Dust mites
  • Mold
  • Foods (peanuts, corn, citrus, milk, wheat, yeasts)
  • Food additives (sulfites, MSG, dyes, other preservatives)
  • Pharmaceutical drugs (ASA, beta-blockers, estrogen, NSAIDs, PCN)


Non-Allergic Causes of Asthma Attacks (2)
  • Additives
  • Air pollution (ozone, smog)
  • Chemical odors (cleaners, nail polish, paint)
  • Coal smoke
  • Cold air
  • Cold drink
  • Cooking fuel (kerosene, natural gas, propane)
  • Emotional stress
  • Exercise
  • Foods (wine)
  • Gastroesophageal reflux (heart burn)
  • Heating units (coal, gas, kerosene, wood)
  • Infection (upper respiratory)
  • Nutritional deficiencies (magnesium, omega-3 fatty acids, selenium, vitamin B6 and vitamin C)
  • Paint fumes
  • Scents (air fresheners, colognes, perfumes)
  • Tobacco smoke
  • Weather changes
  • Wood smoke

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Footnotes
1 American Thoracic Society. Committee on diagnostic standards for non-tuberculosis respiratory disease: Definition and classification of chronic bronchitis, asthma, and pulmonary edema. Am Rev Resp Dis. 1962;85:762.
2 Hamilton K, Roberson K. Asthma. Sacramento, CA. IT Services; 1997.
 
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