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Coleus
(Coleus forskohlii)

 General Info  

Active Forms


Absorption


Dietary Sources


 Dosage Info Back to Top
Dosage Range
250mg (1% standardized extract), 1-3 times a day
-OR-
50mg (18% standardized extract), 1-2 times a day.

Most Common Dosage
250mg (1% standardized extract), 2 times a day
-OR-
50mg (18% standardized extract), 2 times a day.

Dosage Forms
 Adult RDI


Adult ODA
 
 Overview Back to Top
Interactions
Drug/Herb Interactions
• Antihypertensive medications
• Anticoagulant medications
• Antiplatelet medications
• Antihistamines
Coleus is a relatively new medicinal herb in the United States, although it has been extensively researched in India over the last twenty years. There have been numerous studies to support its hypotensive (blood pressure lowering) and spasmolytic effects.(1, 2) Most studies have been done with the isolated extract, forskolin, but current research supports that the whole plant is actually more effective. Many compounds in coleus may act synergistically to improve biological function in the body.
 Toxicities & Precautions Back to Top
General
There is little known risk of toxicity with coleus.

Health Conditions
Based on human data, coleus may aggravate hypotension (low blood pressure), peptic ulcer disease or any bleeding disorder.(3) It should be used with caution in individuals with these conditions.

Pregnancy/Breast-Feeding
If pregnant or nursing, consult a physician before use.

Age Limitations
Do not use in children under 2 years of age unless recommended by a physician.
 Symptoms & Causes of Deficiency  
 Footnotes Back to Top
1 Bhat SV, et al. The Antihypertensive and Positive Inotropic Diterpene Forskolin: Effects of Structural Modifications on Its Activity. J Med Chem. 1983;26:486-92.
View Abstract
2 Baumann G, et al. Cardiovascular Effects of Forskolin (HL 362) in Patients with Idiopathic Congestive Cardiomyopathy -- A Comparative Study with Dobutamine and Sodium Nitroprusside. Cardiovasc Pharmacol. 1990;16(1):93-100.
View Abstract
3 Lindner E, et al. Positive Inotropic and Blood Pressure Lowering Activity of a Diterpene Derivative Isolated from Coleus forskohli: Forskolin. Arzneim-Forsch/Drug Res. 1978;28:284-89.
View Abstract
 
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