Feverfew has gained immense popularity because of its prophylactic effectiveness in relieving migraine headaches.(3) It may take up to a month for therapeutic results to be seen. Once it is discontinued the effectiveness for migraine prevention dissipates. Feverfew is also used for inflammatory conditions such as rheumatoid arthritis,(4) relaxing smooth muscle in the uterus,(5) inhibiting platelet aggregation and blood clotting(6, 7) and fever.(8) The flowers from the plant have been used as a vermifuge. Feverfew has also been used as a natural insecticide.(9)
General No toxicity has been seen in clinical trials in recommended doses.(10)
Abruptly discontinuing use may create a reflex response with migraines.(11)
Allergy Do not use if allergic to pyrethrums. Use with caution in individuals with severe ragweed allergy or allergy to members of the daisy and chrysanthemum family (Compositae).(12)
Health Conditions Based on pharmacology, use with caution in individuals with bleeding disorders.(13)
Pregnancy/Breast-Feeding Based on pharmacology and animal studies, do not use if pregnant.(14)
Age Limitations Do not use in children under 2 years of age unless recommended by a physician.