Arabinoxylane

General Info

Active Forms

Absorption

Dietary Sources

Dosage Info

Dosage Range
General immune support: 2 x 250mg capsules, 2-3 times a day.

Aggressive therapy: 4 x 250mg, 3-4 times a day for 2- 4 weeks, then 2 x 250mg, 2-3 times a day thereafter.

Most Common Dosage
General immune support: 2 x 250mg, 2 times a day.

Aggressive therapy: 4 x 250mg, 4 times a day for 4 weeks, then 2 x 250mg, 2 times a day.

Dosage Forms

Adult RDI

Adult ODA

Overview

Interactions

Drug/Herb Interactions
•	Immunosuppressive medications

Mushrooms have been recognized for their medicinal properties for over five millennia.(1) It was not until the last one-third of the past century that technology was capable of biochemically dissecting traditional medicinal mushrooms and isolating their most active immune enhancing constituents. Immune stimulating constituents isolated from more than 30 mushroom species have reported anticancer action in animals.(2)

Arabinoxylane is a polysaccharide dietary fiber formula from the outer shell of rice bran (hemicellulose B) that has been enzymatically modified with Hyphomycetes mycelia from three different medicinal mushrooms: shiitake, kawaratake, and suehirotake.(3) Arabinoxylane shows promise not only as a general immune supportive agent, but as an adjunctive/supportive therapy for conditions such as cancer and HIV.(4)

Toxicities & Precautions

General
Arabinoxylane has been reported safe in recommended dosages

Allergy
Individuals with allergies to mushrooms should use caution with this supplement.

Health Conditions
Use with caution in renal failure due to high phosphorus content.

Symptoms & Causes of Deficiency

Footnotes

¹ Borchers AT, Stern JS, Hackman RM, et al. Mushrooms, tumors, and immunity. Proc Soc Exp Biol Med. 1999;221:281-293.
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² Wasser SP, Weis AL. Therapeutic effects of substances occurring in higher basidiomycetes mushrooms: a modern perspective. Crit Rev Immunol. 1999;19:65-96.
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³ Ghoneum M, et al. EFFECT OF MGN-3 ON HUMAN NATURAL KILLER CELL ACTIVITY AND INTERFERON- y SYNTHESIS IN VITRO. FASEB JOURNAL. Jun1996;26.
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⁴ Ghoneum M. Anti-HIV activity in vitro of MGN-3, an activated arabinoxylane from rice bran. Biochem Biophys Res Commun. Feb1998;243(1):25-9.
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