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Guo's Coronary Arteriosclerosis Formula
Yang Da Guo, et al. treated 50 cases of angina pectoris with the methods of soothing-liver, regulating-qi, activating-blood, and dredging-collaterals. The formula used contained the following herbs: Chai Hu (Bupleurum), Zhi Qiao (Aurantium Fruit), Jie Gen (Platycodon Root), Yu Jin (Curcuma Root), Fu Shou (Finger Citron), Chuan Xiong (Cnidium), Dang Gui (Chinese Angelica Roots), Fang Feng (Siler), Qian Hu (Pencedanum), Mei Gui Hua (Rose Flower), Ge Gen (Pueraria), Dan Shen (Salvia), and Gan Cao (Licorice). The results of this treatment for angina pectoris were: the treatment was significantly effective in 17 cases, 29 cases had improved, and 4 cases did not respond to the treatment, with a total effectiveness rate of 92%. The treatment results of this formula to ST-T segment changes in ECG examination were that 13 cases had significantly improved, 22 cases improved slightly, and 15 cases did not respond to the treatment with a total effectiveness rate of 70%.(2) Yi Qi Fu Mai Tang
Cao Chuan Ming, et al. used Yi Qi Fu Mai Tang (a decoction for replenishing qi and restoring pulse) in the treatment of 58 cases of senile coronary heart disease complicated with ventricular premature complexes. This formula contained the following herbs: Dang Shen (Codonopsis), Ku Shen (Sophora Root), Huang Qi (Astragalus), Dan Shen (Salvia), Suan Zao Ren (Ziziphus), Chi Shao (Peony Red), Chuan Xiong (Cnidium), Hong Hua (Carthamus), Jiang Xiang (Dalbergia Wood), Wu Wei Zi (Fructus Schisandrae), Gui Zhi (Ramulus Cinnamoni), and Zhi Gan Cao (prepared Licorice). Four weeks constituted one treatment course. No other anti-arrhythmia drugs were used during this time of treatment. The results showed that among the 58 cases treated, 30 cases were significantly improved, 22 improved, and the remaining 6 cases did not respond to the treatment, with a total effectiveness rate of 89.7%.(3) Xue Fu Zhu Yu Tang
Geng Jun, et al. treated 30 cases of coronary heart disease with Xue Fu Zhu Yu Tang (a decoction for removing blood stasis in the chest). This formula contained the following herbs: Tao Ren (Persica), Hong Hua (Carthamus), Sheng Di (Rehmannia), Dang Gui (Chinese Angelica Root), Niu Xi (Achyranthes), Chi Shao (Peony Red), Chuan Xiong (Cnidium), Zhi Qiao (Aurantium), Jie Gen (Platycodon Root), Chai Hu (Bupleurum), and Zhi Gan Cao (prepared Licorice). One therapeutic course consisted of 28 consecutive days. A control group of 20 cases was treated with regular doses of nifedipine, sorbide nitrate, or nitroglycerol whenever an emergency occurred. The total effectiveness rates in the treated and the control groups were: for angina pectoris, 90% and 85% and for ECG improvement, 80% and 75%, respectively.(4) Zhen Wu Tang
Hu Ye Bin used modified Zhen Wu Tang (a decoction for strengthening the spleen-yang) in the treatment of coronary heart disease complicated with heart failure. The formula used contained the following herbs: Hong Shen (Red Ginseng), Dan Shen (Salvia), Shou Fu Pian (prepared Aconitum), Fu Ling (Poria), Bai Shao (White Peony Rood), Bai Zhu (Atractylodes), and Sheng Jiang (Ginger). One dose of the formula in a decoction was administered daily at four takings. Two weeks constituted one treatment course. The results showed that among the 20 cases treated, 6 had significantly improved, 12 improved slightly, and 2 cases did not respond to the treatment, with the total effectiveness rate of 90%.(5) Xiao Xian Xiong Tang
Li Yu Chao treated 28 cases of coronary heart disease with Xiao Xian Xiong Tang (a minor decoction for relieving stuffiness in the chest). This formula contained the following herbs: Ban Xia (Pinellia), Zhi Shi (Immature Bitter Orange), Huang Lian (Coptis), Gua Lou (Trichosanthes Fruit), Dan Shen (Salvia), Ge Gen (Pueraria), and Shan Zha (Crataegus). One treatment course continued for 30 days. The results were: After one course of treatment, 14 cases were significantly improved, 11 cases improved slightly, and 3 cases did not respond to the treatment with a total effectiveness rate of 89.3%.(6) Guan Xing Nao
Feng Ying Xiang used a Guan Xing Nao capsule in the treatment of 33 cases of coronary heart disease complicated with encephalopathy. The formula contained the following herbs: Huang Qi (Astragalus), Dan Shen (Salvia), Dang Shen (Codonopsis), Dang Gui (Chinese Angelica Root), Chuan Xiong (Cnidium), Chi Shao (Peony Red), Shi Chang Pu (Grassleaved Sweetflag Rhizome), Yu Jin (Curcuma Root), Tian Ma (Gastrodia), Ban Xia (Pinellia), and Chen Pi (Citrus). The herbs were ground into a fine powder and then put into capsules to be taken 6-8 g three times a day. 10 days constituted one treatment course. The results were: 16 cases were resolved, 8 cases significantly improved, 5 improved slightly, and 4 cases did not respond to the treatment, with the total effectiveness rate of 87.8%.(7) Fu Fang Dan Shen Di Wan
Ma Hai Yan, et al. used Fu Fang Dan Shen Di Wan (pills of Dan Shen compositae) in the treatment of 112 cases of angina pectoris. 10 pills were orally administered, 3 times a day. Before the beginning of the treatment, the use of all other anti-angina pectoris drugs was terminated for 5 plasma half-life periods. The results showed that, after 1-2 weeks of treatment, 42 cases had significantly improved, 56 cases had improved slightly, and the remaining 14 cases did not respond to the treatment. (8)
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Li Xue Ling, et al. treated 40 cases of coronary disease with acupuncture therapy. The plasma levels of vitamin B2 in patients were significantly decreased and the therapeutic results were satisfactory. The total effectiveness rates were 85.0% for angina pectoris and 67.5% for improving ECG. (9)
Li Bao Liang, et al. treated 34 cases of angina pectoris with acupuncture therapy, and the following back-shu points were selected: Xin Shu (BL 15), Gan Shu (BL 18), and Shen Shu (BL 23). All points were punctured with the twirling vertical lifting-thrusting, and uniform reinforcing-reducing methods. The needles were retained for 25 minutes. One session was conducted each day. 12 days constituted one treatment course. A control group of 28 cases were treated only with a Guan Xin Dan Shen Pianin tablet, which contained Dan Shen (Salvia), San Qi (Notoginseng), and Jiang Xiang (Dalbergia Wood). The results of the treatment after 24 days were evaluated. The clinical effectiveness rate was 91.18% in the acupuncture group, and 82.14% in the control group (P>0.05). ECG improvement rates were 79.41% and 46.43%, respectively (P<0.05). In comparison between two groups, the clinical effectiveness rate in the acupuncture group was higher than that of the control group, but without statistical significance. However, regarding the ECG improvement rate, the treatment group was much higher than the control group, and difference was statistically significant.(10)
Yu Li, et al. used acupuncture therapy in the treatment of 98 cases of coronary heart disease. The needle was inserted into point Nei Guan (PC6) until the needling sensation was felt, and then it was retained for 15 minutes. All the patients received acupuncture therapy once a day and ten days established one treatment course. During this treatment period, no drugs were administered. When comparing the results of ECG examination before and after the treatment at the end of three courses of acupuncture therapy, there were significant statistical differences as to the descending of S-T segment and the decrease of heart rate (P<0.01).(11)
Acupoint Plastering Therapy
Dai Ju Yun, et al. used acupoint adhesion therapy for the treatment of angina pectoris in 95 cases, using Dan Qi Yi Xin adhesive plaster, which contained extracts of Dan Shen (Radix Salviae miltiorrhizae), Huang Qi (Radix Astragali seu Hedysari) etc. The plasters were adhered to the following points: Tan Zhong (CV17), Shen Que (CV18), Xin Shu (BL15 left side), and Zhi Yang (GV9). All the patients received treatment once a day. Four weeks constituted one treatment course. Two control groups were treated with acupoint adhesion with nitroglycerin in one group of 20 cases, and oral administration of Dan Shen tablets in another group of 30 cases, respectively. The results were that the effectiveness rate for relieving chest pain in the treatment group was 91.1%, and those of the two control groups were 95% and 80%, while the ECG effectiveness rate of the treatment group was 68.6%, and for two control groups were 64.7% and 62.5%.(12)
Gao She Guang, et al. treated angina pectoris with She Xiang Tong Bi plaster stuck at points of Tan Zhong (CV17) and Nei Guan (PC6) on both sides. The plasters were changed every three days. 15 days constituted one treatment course. The results showed that in this series of 130 cases, 111 cases were clinically resolved, 17 cases had improved, and 2 cases did not respond to the treatment. The total effectiveness rate was 98.5%.(13)
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